pycnogenol benefits dr axe

Ask your doctor for advice. In a study of 61 ADHD children, pycnogenol reduced hyperactivity, improved attention, and motorics after 1 month. Procyanidins are chain-like structures consisted of catechins similar to some found in green tea (the green tea catechins that do not have 'gallate' in their names). Pycnogenol is a patented extract of the French maritime pine bark (Pinus pinaster). Pycnogenol may have benefits for heart and artery health. Not bad. Herbal supplements are not regulated by the Food and Drug Administration (FDA), so they may not be up to the same safety standards as medications that have gone through clinical testing and drug trials. One study found that Pycnogenol may reduce the activity of the inflammatory enzymes COX1 and COX2, similar to how NSAID drugs work. The staff there can often answer any questions you have and give you more information about specific brands. Pine bark extract contains active ingredients that can also be found in peanut skin, grape seed, and witch hazel bark. If youre native to Oregon, you likely know all about marionberries. This review noted that pine bark extract may also help with: In addition to its skin-healing properties, pine bark extract also shows promise for helping children manage ADHD symptoms. Boost gastrointestinal health. He learned about the seemingly omnipotent antioxidant within it and how those antioxidants increase the absorption of vitamin C. Continued research showed that the pine bark contained flavonols and bioflavonoids, which hold tissue-repairing properties. This condition is due to the pooling of blood in the veins of the lower legs. Inhibits platelet aggregation like low-dose aspirin. The outcome showed significant healing when compared to those subjects who were not given any drug or remedy, concluding that Pycnogenol may be an effective remedy for healing of surgery-related lesions. Pycnogenol is a patented formulation of Pine Bark Extract which is standardized to 65-75% Procyanidin compounds by weight. Grape seed extract may have heart-health benefits. It also lessened the amount of asthma medication they needed. Pycnogenol seems to help with asthma and allergies. Results showed that one month of Pycnogenol led to a significant reduction of hyperactivity with improvement in attention and visual-motor coordination and concentration, as compared to no positive effects in the placebo group. According to a large analysis, Pycnogenol may reduce osteoarthritis symptoms and pain short-term [45, 46]. Neuroprotective effect of Pycnogenol® following traumatic brain injury. Because of its anti-inflammatory effects, nattokinase has been used to help with pain from arthritis, including that of rheumatoid arthritis. In some people lung inflammation is caused by leukotrienes chemicals that are released by the body after a person encounters allergens. Flavonoids and proanthocyanidins within these fruits can . Pycnogenol led to a reduction of muscle cramps from 4.8 a week to 1.3 at week four. A trial of children with ADHD found that Pycnogenol may improve attention, possibly by increasing the total antioxidant status and reducing DNA damage. New studies show Pycnogenol can prevent or reverse the oxidative damage that produces blood vessel disease 4, metabolic syndrome 20, diabetes 20,24, and neurodegenerative disorders 23,24. Although the preliminary studies show many health benefits with the use of Pycnogenol, future larger and better studies are needed. Vertigo. Pycnogenol (200 mg/day) may reduce muscle cramps and pain according to a study of 66 healthy people, athletes, and those with venous problems after 4 weeks. Pine bark extract can be found in liquid, tablet or capsule form containing 85 percent to 90 percent OPCs. Pycnogenol lowered leukotrienes as well. Results failed to show any efficacy of Pycnogenol or methylphenidate when compared to placebo. In mice, luteolin prevented inflammation and allergic response in the lungs and nose by inhibiting inflammatory cytokines: IL-4, IL-5, and IL-1 3 []. In another good study, 48 patients with diabetes and high blood pressure on ACE inhibitors were randomized to receive either Pycnogenol 125 mg daily or placebo for 12 weeks. According to a study of 11 patients with lupus, pycnogenol may reduce symptoms, inflammation, and oxidative stress [54]. editor, The Gale Encyclopedia of Alternative Medicine, third edition, 2009. A clinically studied blend of Pycnogenol and a special bilberry extract (called Mirtogenol ) has been shown to provide benefits for vision and eye health. New research shows . The active ingredients in pycnogenol can also be extracted from other sources, including peanut skin, grape seed, and witch hazel bark. It had the best results when combined with compression stockings, but worked just as well alone [28]. But what makes this miracle ingredient so amazing? . Pycnogenol can help control blood pressure, which helps improve overall heart health. Some of the top lutein-rich foods to include in your diet are dark leafy greens like spinach and kale, broccoli . Pycnogenol lotions applied postirradiation reduced this immunosuppression to 22% (0.05% Pycnogenol) and 13% (0.1% Pycnogenol). According to researchers, it may help prevent the rise in free radicals typically seen after exercise, which could cause muscle fatigue and damage [9]. In the study, many of the participants on Pycnogenol reduced their dosage of high-blood-pressure medication (nifedipine) [37]. Pycnogenol (100 mg/day) given to 44 older healthy people with high oxidative stress improved cognitive function, attention, mental performance, and reduced oxidative stress after 12 months [21]. Some studies have suggested it may modestly improve blood pressure, cholesterol, and C-reactive protein. Optimal doses of pycnogenol have not been set for any condition. This plant extract also shows promise in such far-flung conditions as traumatic brain injury 40,41, skin problems 37, pain syndromes 38,39, and even tinnitus . Studies have found that when taken along with an inhaler, Pycnogenol can reduce leukotrienes, helping to relieve lung inflammation and limit frequency of inhaler use., Many people develop osteoarthritis as they age. Pycnogenol may help with other conditions as well. Purity and potency of Pycnogenolare continuously monitored . In a third study, 19 men with fertility problems were given 200 mg Pycnogenol daily for 90 days. Pycnogenol improved symptoms, circulation, and reduced complications in 156 people with deep vein thrombosis (blot clots in deep leg veins) in a 12-month study. You can learn more about how we ensure our content is accurate and current by reading our. Buy Healthy Origins Pycnogenol 100 mg (Nature's Super Antioxidant, Non-GMO, Gluten Free, Cardiovascular Support), . , Allergy: "Leukotriene E4 plasma levels in adult asthmatic patients with variable disease severity. It has been studied for its effects on everything from mental function to treating high blood pressure. The crew fell extremely ill from scurvy, an extreme lack of vitamin C. Cartiers crew crossed paths with a Quebec Indian who encouraged them to drink a tea made from pine bark and needles. The researchers concluded that pine bark extract may increase production of hyaluronic acid and collagen, which are both found in many popular antiaging products. In patients with chronic venous insufficiency, the number of muscle cramps decreased from 6.3 to 2.6; in athletes from 8.6 to 2.4. Regardless of what youre using it for, its best to start with the lowest possible dose. There havent been enough studies yet to change practice protocols for treating children. Blazs G, et al. Moreover, Pycnogenol group either reduced or discontinued the use of asthma drugs. The 2012 study on the anti-aging benefits of Pycnogenol is commonly-cited by anti-aging supplement manufacturers. For most people, pine bark extract doesnt cause any side effects. If a blood clot blocks the normal blood flow, it is known as thrombosis. Several studies show how Pycnogenol helps block platelet formation and thus helps prevent thrombosis. Cigarette smoking increases platelet aggregation. Pine bark extract has been studied with regard to its ability to help diabetic patients. There is a seemingly growing problem with skin exposure to ultraviolet radiation and the confusion of how to get vitamin D from the sun while avoiding these skin-damaging rays. In contrast, bleeding still occurred in the control group [61]. Pycnogenol is a natural plant extract originating from the bark of the maritime pine that grows along the coast of southwest France and is found to contain a unique combination of procyanidins . A study of 50 mildly infertile men found that a combination of L-arginine, L-citrulline, roburins, and Pycnogenol (Prelox R) may improve sperm quality, volume, and concentration [75]. He later extracted proanthocyanidins from the European coastal pine tree, which he named Pycnogenol.. A combination product with Pycnogenol (Lady Prelox) improved sexual function in a clinical trial of 83 healthy postmenopausal women after 8 weeks. Speak with your doctor before supplementing. Work with your pediatrician to see if there are contraindications for each child. However, in all the above studies insulin levels did not change. As a skin cream, its safe to use for about seven days. In the study, the placebo group had higher IgE antibodies to the birch allergen than those who took Pycnogenol during the allergy season [17]. Pycnogenol significantly reduced the swelling as well as the feeling of heaviness. Commonly called arthritis, osteoarthritis is caused when the cartilage on your joints begins to wear down. It can also be used for local application on the skin without the risk of side effects. Moreover, Pycnogenol treatment led to an increase in sperm count and testosterone levels with lowering of blood pressure and cholesterol levels. Pycnogenol French maritime pine bark extract acts as a potent blend of antioxidants, it is a natural anti-inflammatory, stimulates generation of collagen and hyaluronic acid and help with natural dilation of blood vessels by supporting production of nitric oxide. Pycnogenol acts as a sustained-release formulation. The standard dose appears to be 100-200 mg/day. Its been noted that taking OPCs and vitamin C supplements at the same time could increase blood pressure if you have hypertension. In those treated with Pycnogenol, the edema score was increased by 17.9% versus an increase of 58.3% in the control group. The remaining compounds are phenolic acids, which may also have antioxidant activity [1, 2]. Pycnogenol can help control blood pressure, which helps improve overall heart health. Dr. Drew explains the benefits of probiotics for the gut microbiome and talks about the rise of leaky gut, and Dr. Steve shares how emotional stress can have real physical effects on the heart. Potential for allergy when taken orally or used on the skin. However, these studies appear to be methodologically sound and reliable, with no blatant errors in the study design and data collection. It is standardized to contain 65-75% procyanidins, a class of polyphenols and flavonoids like those found in blueberries, wine, grape skin, citrus, and cocoa. For children with ADHD, research suggests that symptoms start to return after about a month without taking maritime pine, so taking periodic breaks shouldnt make it any less effective. The supplement significantly reduced hot flashes, night sweats, mood swings, irregular periods, loss of libido, and vaginal dryness. Pycnogenol (up to 200 mg/day) may improve asthma and reduce inflammatory asthma markers in the blood, leukotrienes, after 4 weeks, according to a randomized placebo-controlled trial of 26 asthma patients [14]. Can you get pycnogenol naturally from foods? Pycnogenol is the leading ingredient in Isotonix OPC-3, Market America's best-. Our team includes licensed nutritionists and dietitians, certified health education specialists, as well as certified strength and conditioning specialists, personal trainers and corrective exercise specialists. Prenatal nutrition can be confusing. Another one of its exemplary effects is helping manage blood pressure levels. Pycnogenol, an extract of French maritime pine bark, helps the body fight normal aging by supporting vascular health and healthy circulation. Learn about all the potential benefits of Pycnogenol and find out which ones are most supported by science. Pycnogenol seems well-tolerated for use in adults for up to 6 months. Taking pycnogenol daily for 2 months seems to slow or prevent further worsening of retinal disease caused by diabetes, atherosclerosis, or other diseases. Pycnogenol also potentially improved cognitive function in 78 people with mild cognitive impairment. This supplement possibly activates the immune system. Pycnogenol reduced foot swelling in 79% of the patients, versus one percent in the placebo group. Its likely that muscle recovery time improved as well due to the high antioxidants pine bark extract contains. According to some researchers, Pycnogenol may lower blood pressure by relaxing blood vessels, reducing free radicals, and lowering inflammation. Sort By. While it may seem intimidating at first, counting macros is a common Erythritol is now one of the most popular natural zero-calorie sweeteners available. This condition can be temporary or permanent however, some studies have indicated that pine bark extract may help alleviate these symptoms due to its high presence of antioxidants. Pycnogenol may stimulate the immune system. are clickable links to medically peer-reviewed studies. Tongkat ali is an herbal remedy suggested to treat various ailments, including low testosterone and male infertility. Pycnogenol (150 mg/day) reduced LDL and increased HDL cholesterol in a trial of 25 healthy people after 6 weeks [55]. It may cause side effects such as: Risks. If you are thinking of taking Pycnogenol for a serious health condition like asthma or high blood pressure, check with your doctor., People who have autoimmune conditions like multiple sclerosis or lupus should talk to their doctor before trying Pycnogenol. Thirty patients were treated with 150 mg of Pycnogenol a day and the other 10 patients with placebo for a period of two months. A small 2012 study on postmenopausal women found that pine bark extract improved hydration and elasticity of skin. It also may help those on blood pressure medications to reduce their dose [32]. Pycnogenol was featured on The Dr. Oz Show in January 2013, . The U.S. Food and Drug Administration (FDA) does regulate dietary supplements; however, it treats them like foods rather than medications. Pine bark extract provides many benefits to the skin, including reducing the signs of aging. Pycnogenol has several benefits to your health and beauty. , Improves Symptoms Associated With Menopause, A number of women experience physical discomfort due to symptoms of menopause. Grape seed extract may be more beneficial for those who are obese. Pine bark distill has been studied regarding its relationship to exercise performance, oxidative stress and excitement to torso that has been imposed by exercise. A clinical trial of 57 ADHD children found that daily Pycnogenol (1 mg/kg) for one month may reduce hyperactivity symptoms. There were 88 in the control group and 81 in the Pycnogenol group. The treatment was four 50 mg capsules of Pycnogenol. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. However, it is also important to see beyond the pyncogenol marketing campaign and understand the possible dangers associated with this natural supplement. Pycnogenol treatment lowered the ACE-inhibitor dose required to control blood pressure, and lowered fasting glucose levels as well. - Apply a hot compress to the anus or soaking it in a shallow tub of hot water several times a day. 1 Anti-Aging Beverage, An surprisingstudy found that pine bark extract was far better than aspirin at inhibiting smoking-induced clotting, using lower amounts without the bleeding often found when using aspirin. Pycnogenol is officially extracted from the French maritime pine (Pinus pinaster), which grows in the southwest coast of France. Pine bark extract is usually taken by mouth in capsule form. Researchers suggest it may boost sustained attention, memory, executive functions, mood, and reduce oxidative stress [19]. Another study of 47 women found that supplementing with 30 mg Pycnogenol twice daily for over 1 month may reduce menstrual pain [73]. The same study showed that a single, 200-mg Pycnogenol dose remained effective over six days in preventing cigarette-induced enhanced platelet aggregation. If you knew you could resolve your erectile dysfunction and, therefore, naturally remedy impotence issues, wouldnt you? There is insufficient evidence to support the use of Pycnogenol for any of the uses listed below. Researchers suggest this effect may be due to reduced dopamine and adrenaline levels and increased glutathione levels. These antioxidants scavenge those damaging free radicals in an effort to eliminate them, ultimately preventing disease. It seems to lower blood pressure and improve blood flow to the legs. Almost 400 years later, Dr. Jacques Masquelier from France came across Cartiers account and started to look for the active ingredients from the bark of the tree. In one clinical trial of 156 osteoarthritis patients, pycnogenol reduced pain, stiffness, swelling, and improved joint function after 3 months. Depending on the extraction process and the source Pinus species used (P. radiata or P. pinaster), the exact composition will vary. Debra Rose Wilson, PhD, MSN, RN, IBCLC, AHN-BC, CHT. Another study in 2012 showed that Pycnogenol alone, at a dose of 75 mg/day, increased skin hydration by 8% after just 6 weeks; in women with dry skin at baseline the increase was 21%. A study of 58 people with high blood pressure suggests that even lower doses (100 mg/day) may improve blood vessel health and reduce markers of high blood pressure (endothelin-1) after 12 weeks. Your email address will not be published. Pycnogenol also treatment improved blood vessel function. Diindolylmethane, or DIM for short, is a plant indolea plant compound with health-promoting properties. The combination of Panax ginseng and vitamin E also appears to have an effect. High levels of both of these are considered risk factors for heart disease. Diabetes-associated small blood vessel changes is the leading cause of diabetic ulcers. Symptoms include swelling in ankles and legs, discolored skin and, if the skin is broken, the development of leg ulcers. The effects of the pine bark extract showed significant lower levels of blood glucose and improved endothelial function when compared to placebo, concluding that supplementation of Pycnogenol for . But, as you know, going for the natural approach can make a huge difference in overall health. ", Mayo Clinic: High blood pressure (hypertension)., Panminerva Medica: "Pycnogenol improvements in asthma management. Due to its anti-inflammatory properties, luteolin is being researched as a potential complementary treatment for multiple . A randomized, double-blind, placebo-controlled study of 60 patients aged six to 18 years old, was conducted over three months during which patients were randomly assigned to receive either Pycnogenol or placebo. DOI: Scheff SW, et al. In a good-quality study, 100 patients with osteoarthritis of the knee were treated for three months either with 150 mg of Pycnogenol a day or placebo. Pycnogenol suppresses inflammation and regulates the production of nitric oxide - a . A trial of 84 people found that both Pycnogenol oral supplements and creams (0.5%) may prevent hemorrhoids from bleeding during acute attacks after 7 days. There are also several other natural ADHD remedies you can try. In another study, 45 men with ED were given 1.7 grams of L-arginine a day during the first month, 40 mg Pycnogenol twice daily during the second month, and the dose increased to three 40-mg Pycnogenol doses daily during the third month. You can refer to the National Institutes of Healths dosage guidelines for specific conditions. The Best Supplements for Healthy Digestion, How to Get the Protective Power of Vitamin K. Study participants took pine bark extract as a supplement, and it was found to be most effective in women who started out with dry skin. Your email address will not be published. Blood clots form as a result of platelet aggregation, which is the platelets in the blood clumping together. Various brands of pycnogenol are available. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. Researchers from the study suggest that low Pycnogenol dosage and short study duration may explain the lack of benefits [44]. These wounds occur most frequently in hospitals or in those with weakened immune systems, such as after surgery. The flesh of the grape contains approximately 1/20th-1/100th of the total antioxidant capacity of the seed or the skin. As a skin powder, however, you can use it safely for up to six weeks. It also reduced LDL cholesterol at a slightly lower dose (125 mg/day) in those with type 2 diabetes in a clinical trial of 48 people after 12 weeks. Symptoms of menopausal syndrome, also known as climacteric syndrome, include: hot flashes; chills; headache; and depression. One study suggests that Pycnogenol has no effect when given just 3 weeks beforehand, as it possibly requires a lag time to stabilize the immune response [17]. Used early on, it may prevent eye damage and blindness from diabetes [34]. (2006). Finally, research suggests that Pycnogenol may improve triathlon time while possibly reducing cramps and post-running pain [10]. Dizziness. 3. Pycnogenol has been well-tolerated in most studies performed thus far. Pine bark extract has been studied regarding its relationship to exercise performance, oxidative stress and inflammation to body that has been imposed by exercise. Start with a low dose so you can be sure it doesnt cause any side effects. Pycnogenol alleviated adverse effects in cancer patients, Pycnogenol improved working memory in older adults, Pycnogenol lowered the use of analgesic drugs in dysmenorrhea (severe menstrual pain), Pycnogenol reduced symptoms in endometriosis comparable to leuprorelin, the standard drug for this condition, Pycnogenol was found to be effective for sun-caused hyperpigmented skin, Pycnogenol reduced the inflammation in lupus patients, Pycnogenol reduced gingival bleeding and plaque formation. In a clinical trial of 116 women, Pycnogenol (60 mg/day) reduced menstrual pain and the need for additional painkillers, taken over 2 cycles. Considering that about 1 of 3 adults in the U . Pycnogenol has been shown to help relieve the pain associated with osteoarthritis by keeping blood chemicals from attacking the cartilage. For allergies: 50 milligrams twice daily. In another trial, 30 people with type 2 diabetes received a range of pycnogenol doses. For asthma in children: 1 milligram per pound of body weight given in two divided doses. In a study of 33 people with severe osteoarthritis, pycnogenol (200 mg/day) reduced inflammatory markers after 3 weeks. Patients were given 100 milligrams of Pycnogenol, a branded version of pine bark extract, for 12 weeks, with continued anti-diabetic treatment. from the bark of the French maritime pine tree. Pycnogenol treatment led to significantly better improvement in the lung function and asthma symptoms. Is Garcinia Cambogia Safe for Weight Loss? The researchers of the study propose that pycnogenol may reduce pain and cramps during retraining and rehabilitation in people with blood vessel problems [11]. In clinical research, doses up to about 300 mg/day have been used for up to one year without major safety concerns [33, 37]. A trial of 53 students found that pycnogenol may improve cognitive function, memory, attention, mood, and mental performance after 8 weeks [20]. People who use the supplement along with their traditional medication usually take smaller doses than those who only take the supplement. Pine bark extract appears to reduce the creation of free radicals, which are molecules linked to several skin conditions. DOI: Gulati OP. Also, be sure to talk with your doctor first if you have an underlying medical condition or take other medications. In a study of 20 postmenopausal women, 12 weeks of pycnogenol supplementation improved hydration and elasticity of the skin. Two doses of 100 mg of Pycnogenol were taken two to three hours before flights and two additional capsules taken six hours later then one capsule the next day. Add to Cart. Its quality is specified in the United States Pharmacopeia [3]. Researchers suggest that it may have stronger benefits than elastic compression stockings. Lower the risk of Alzheimer's disease. Its best to check with your doctor about the dosage, based on the symptoms you have and other possible conditions, prior to taking either pine bark extract or Pycnogenol. Still, more research is needed to better understand these findings and pine bark extracts role in reducing damage from head trauma. In one study, people with high blood pressure were examined to see how the supplement impacted their blood pressure. We avoid using tertiary references. In the study, women taking Pycnogenol were more satisfied and compliant to the regimen [24]. In 7 volunteers, Pycnogenol (300 mg) for 5 days may reduce the activity of a crucial inflammatory gene (NF-B) [53]. Disease of the retina in the eye. Pycnogenol; Pycnogenol. It also may increase the activity of genes that make collagen and hyaluronic acid in the body [64]. A small 2017 study examined the effects of pine bark extract in treating cardiovascular risk factors associated with menopause. (2006). $47.99. Research suggests that taking pycnogenol improves mental function and memory in both young adults and the elderly. Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung disease caused primarily by tobacco use. Treatment of ADHD with French maritime pine bark extract, Pycnogenol [Abstract]. The same ingredient can be found in grapeseed oil, the skin of peanuts and witch hazel bark. In a good-quality study, 77 patients with osteoarthritis were treated with 100 mg of Pycnogenol daily and 79 patients were treated with placebo for three months. The review found evidence that pine bark extract may: Similar to its neuroprotective benefits, the metabolic benefits of pine bark extract seem to be related to its antioxidant and anti-inflammatory properties. Pycnogenol completely normalized function. (2015). According to a study in 59 cancer patients, Pycnogenol (150 mg/day) may reduce side effects associated with radiation or chemotherapy, including mouth soreness and ulcers, mouth and eye dryness, nausea, vomiting, diarrhea and weight loss [78].

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