venofer dosing calculator

This website is intended for use by US healthcare professionals only. Administer while the patient is in a reclined or semi-reclined position. The above information is provided for general Privacy Policy, Use 500 mg for adults and children 35 kg; use 15 mg/kg if <35 kg. Applies only to oral form of both agents. Individual plans may vary Either decreases levels of the other by inhibition of GI absorption. Initial infusion rate. Results: Twelve children (6 females) aged 1.2-14 years (median age 8.9 years) received at least one dose of . I. Hypotension following administration of Venofer may be related to rate of administration and/or total dose delivered. Applies only to oral form of both agents. Applies only to oral form of both agents. Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. Dr. Ganzonis primary research is focused on iron deficiency and plasma iron transport. Monitor Closely (1)nizatidine will decrease the level or effect of iron sucrose by increasing gastric pH. Keep all medical and lab appointments. Dosing: (a) Divide calculated total cumulate dose . Applies only to oral form of both agents. Minor/Significance Unknown. Minor/Significance Unknown. Use INFeD only in patients in whom clinical and laboratory investigations have established an iron deficient state not amenable to oral iron therapy. Applies only to oral form of both agents. Applies only to oral form of both agents. Applies only to oral form of both agents. Minor/Significance Unknown. Oral iron therapy is the first method while IV therapy comes in place when there are contraindications or the body doesnt respond to the oral one. 2) Koch TA, Myers J, Goodnough LT. (2015) Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations. Venofer [package insert]. Test Dose: Not required. Adverse pregnancy outcomes associated with IDA include increased risk for preterm delivery and low birth weight. Applies only to oral form of both agents. The dosage of Venofer is expressed in mg of elemental iron. Applies only to oral form of both agents. Iron stores 500 mg for body weight greater than or equal to 35 kg (77 lbs) and 15 mg/kg for body weight less than 35 kg. Deferoxamine chelates iron. WARNING: RISK FOR SERIOUS HYPERSENSITIVITY/ANAPHYLAXIS REACTIONS Fatal and serious hypersensitivity reactions including anaphylaxis have occurred in patients receiving Feraheme. Iron deficiency anemia calculator (diagnosis), Iron deficiency anemia vs. Chandler G, Harchowel J, Macdougall I. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Echocardiogram Z Score (NEW)(BETA TESTING) Edinburgh Postnatal Depression Scale. Calculosaurus | Medical calculators for obstetrics and gynaecology Use the menu to browse through our clinical calculators. Use Caution/Monitor. Applies only to oral form of both agents. 2 *Venofer is an iron replacement product indicated for the treatment of iron deficiency anemia in patients with CKD. Administer ciprofloxacin at least 2 hours before or 6 hours after using these products. The factor 2.4 comes about from the calculation that the total iron content of hemoglobin is 0.34%, the blood volume accounts for 7% . Minor/Significance Unknown.iron sucrose increases levels of calcium acetate by enhancing GI absorption. Serious - Use Alternative (1)iron sucrose will decrease the level or effect of baloxavir marboxil by cation binding in GI tract. This cost includes the fee charged by the pharmacy. Uses for Iron Sucrose Max Dose. In the text below the tool there is more information on how the iron deficit is calculated. Last updated on Jun 1, 2022. Iron deficiency can occur at any stage of life, due to physiological demands, for example, during pregnancy, childhood growth or prolonged periods of sickness. DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. Excessive therapy with parenteral iron can lead to excess storage of iron with the possibility of iatrogenic hemosiderosis. The following table present normal hemoglobin ranges: There is another equation for iron deficit that can be used to calculate replenishment needs, that of Ganzoni, which takes into account iron stores as well and that can be found in the iron deficit calculator. Applies only to oral form of both agents. Applies only to oral form of both agents. Serious - Use Alternative (1)iron sucrose decreases levels of tetracycline by inhibition of GI absorption. Use Caution/Monitor. Congenital Pulmonary Airway Malformation Volume Ratio (CVR) Calculator -. Taking the case of a patient weighing 75 kg (165.3 lbs) with a target hemoglobin value of 13 g/dL (130 g/L or 8.07 mmol/L), an actual hemoglobin of 9.5 g/dL (95 g/L or 5.9 mmol/L) and iron stores of 500 mg, the iron deficit is: Iron deficit = 75 x (13 9.5) x 2.4 + 500 = 1,130 mg. Mean change in Hgb from baseline to Week 5 2,5 Venofer is manufactured under license from Vifor (International) Inc., Switzerland. These adverse reactions have occurred up to 30 minutes after the administration of Venofer injection. Hemodialysis-dependent: 0.5 mg/kg IV q2weeks for 12 weeks; not to exceed 100 mg/dose, Non-dialysis dependent or peritoneal-dependent (on erythropoietin): 0.5 mg/kg IV q4weeks for 12 weeks; not to exceed 100 mg/dose, sodium sulfate/?magnesium sulfate/potassium chloride, sodium sulfate/potassium sulfate/magnesium sulfate, Serious hypersensitivity reactions reported, including anaphylactic-type reactions, some of which have been life-threatening and fatal, Patients may present with shock, clinically significant hypotension, loss of consciousness, and/or collapse, If hypersensitivity reactions or signs of intolerance occur during administration, stop infusion immediately, Monitor patients for signs and symptoms of hypersensitivity during and after administration for at least 30 minutes and until clinically stable following completion of the infusion, Animal reproduction studies of iron sucrose administered to rats and rabbits during period of organogenesis at elemental iron doses equivalent to maximum recommended human dose based on body surface area revealed no evidence of harm to the fetus; adverse outcomes in pregnancy occur regardless of health of mother or use of medications, Iron deficiency anemia during pregnancy should be treated; untreated IDA in pregnancy is associated with adverse maternal outcomes such as post-partum anemia; adverse pregnancy outcomes associated with IDA include increased risk for preterm delivery and low birth weight, HD-dependent and non-dialysis-dependent CKD: Dilute with up to 100 mL of 0.9% NaCl, PD-dependent CKD: Dilute with up to 250 mL of 0.9% NaCl, Undiluted: Administer by slow IV injection over 2-5 min, Diluted solutions: Administer IV over 15 min, Undiluted: Administer by slow IV injection over 5 minutes, Diluted solutions: Administer IV over 5-60 minutes, Store in original carton at 20-25C (68-77 F); excursions permitted to 15- 30C (59-86F), Syringe: Store at room temperature (25C) or under refrigeration (4C) for up to 7 days, IV infusion: Store at room temperature (25C) for up to 7 days. Our dosage calculator can help you with this as well. * Adapted from the KDIGO Clinical Practice Guideline for Anemia in Chronic Kidney Disease. Reactions have occurred following the first dose or subsequent doses of Venofer. Separate by at least 4 hours. Am J Kid Dis 2001; 38 988991. Suggested regime: Prescribing instructions Prescribing a single/first dose: Most Use Caution/Monitor. This information is not individual medical advice and does not substitute for the advice of your health care professional. Venofer treatment may be repeated if necessary. Minor/Significance Unknown. calcium chloride decreases levels of iron sucrose by inhibition of GI absorption. We first individually analyzed 5 clinical studies, averaging the total iron deficit across all patients utilizing a . 5. iron sucrose will decrease the level or effect of sarecycline by inhibition of GI absorption. You can further save the PDF or print it. 3. Use Caution/Monitor. Indicated for treatment of iron deficiency anemia associated with chronic kidney disease, Hemodialysis-dependent CKD: 100 mg elemental iron IV (injection or infusion over 2-5 min) per dialysis session not to exceed total cumulative dose of 1000 mg divided in 3 doses/week, Non-dialysis-dependent CKD: 200 mg IV injection for 5 doses in over 14 days (cumulative 1000 mg in 14-day period), Peritoneal dialysis-dependent CKD: 300 mg IV infusion (1.5 hr) for 2 doses 14 days apart, THEN 400 mg IV infusion (2.5 hr) 14 days later (cumulative 1000 mg divided in 3 doses/week), Indicated for maintenance treatment of iron-deficient anemia associated with chronic kidney disease, <2 years: Safety and efficacy not established, Iron replacement treatment in pediatric patients has not been established. (See also Notes section. Only administer Venofer when personnel and therapies are immediately available for the treatment of serious hypersensitivity reactions. dexlansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Sodium ferric gluconate (Ferrlecit) 62.5 mg . Applies only to oral form of both agents. Minor (1)gymnema decreases levels of iron sucrose by inhibition of GI absorption. In a randomized, open-label, dose-ranging trial for iron maintenance treatment with Venofer in pediatric patients with CKD on stable erythropoietin therapy [see Clinical Studies ( 14.7)], at least one adverse reaction was experienced by 57% (27/47) of the patients receiving Venofer 0.5 mg/kg, 53% (25/47) of the patients receiving Venofer 1 mg . Discuss the risks and benefits with your doctor.This medication passes into breast milk. Modify Therapy/Monitor Closely. In: Koda-Kimble & Young's Applied Therapeutics: The Clinical Use of Drugs. Iron Deficiency In Pregnancy Calculator, Mean Corpuscular Hemoglobin Concentration (MCHC) Calculator. Use Caution/Monitor. Avoid or Use Alternate Drug. Case G. Maintaining iron balance with total-dose infusion of intravenous iron dextran. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. Avoid or Use Alternate Drug. 1. Minor (1)iron sucrose decreases levels of manganese by inhibition of GI absorption. Read our. The two formulas used are presented below: Iron deficit in mg = Weight in kg x (14 Hb in g/dL) x 2.145, Volume of product required in mL = Iron deficit in mg / C in mg/mL. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. Separate dosing of tetracyclines from these products. Both the 200- and 300-mg doses of IV iron sucrose administered over 2 hours appear to be safe. 0.5 mg/kg/min (0.005 mL/kg/min) Maximum infusion rate (if tolerated) Increase to 8 mg/kg/min (0.08 mL/kg/min) Monitor the patient's vital signs throughout the infusion. Applies only to oral form of both agents. 1996 Aug;11(4):139-46. Monitor Closely (1)iron sucrose will decrease the level or effect of sarecycline by inhibition of GI absorption. Applies only to oral form of both agents. LBW = Lean body weight in kg. 1 ,*. iron sucrose decreases levels of penicillamine by inhibition of GI absorption. J Lab Clin Med. iron sucrose decreases levels of manganese by inhibition of GI absorption. . VENOFER at IV doses up to 15 mg iron/kg/dose [about 10 times the maximum recommended human dose for a 70 kg person] given three times a week was found to have no effect on fertility . Applies only to oral form of both agents. Use Caution/Monitor. View the formulary and any restrictions for each plan. March 2, 2015 [IRON SUCROSE REQUIREMENT CALCULATION FOR SEVERE ANEMIA] DPMU Anantapuramu | National Health Mission 1 Formula for calculating the required dose of Iron sucrose 2.4 X Pre-pregnancy Weight in Kgs X Hb% deficit{11-actual Hb%} in mgs Plus Iron required to replenish the iron stores = 500mg Prepregnancy Weight = 45 kgs . Equations used: 1] Calculation of the Total Iron Deficit: Total iron deficit [mg] = body weight [kg] x (target Hb-actual Hb) [g/dl] x 2.4 + depot iron [mg]. Do not dilute to concentrations below 1 mg/mL [see How Supplied/Storage and Handling [16.2].) 2000 Jan;22(1):39-43. Do not double the dose to catch up. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. Use Caution/Monitor. Minor/Significance Unknown. calcium acetate decreases levels of iron sucrose by inhibition of GI absorption. . iron sucrose decreases levels of mycophenolate by inhibition of GI absorption. Use Caution/Monitor. For males: LBW = 50 kg + 2.3 kg for each inch of patients height over 5 feet For females: LBW = 45.5 kg + 2.3 kg for each inch of patients height over 5 feet Administration: I. Found in multiple references. Anaphylaxis may occur with IV iron and resuscitation facilities should be available.11 It would appear that iron polymaltose may have a higher incidence of severe systemic reactions than iron sucrose and ferric carboxymaltose. Use Caution/Monitor. Treatment of anemia due to iron deficiency. Applies only to oral form of both agents. Applies only to oral form of both agents. The dosing for iron replacement treatment in pediatric patients with NDD-CKD or PDD-CKD has not been established. Schweiz Med Wochenschr; 100(7):301-3. When iron sucrose was administered at deliberate overdoses to rabbit dams (up to 215 mg/kg/day) marked fetal/placental iron overload was noted. FERAHEME was non-inferior to Venofer (iron sucrose) in mean Hgb rise from baseline 2,5. Administer on 5 different occasions over a 14 day period. Monitor Closely (1)iron sucrose decreases levels of thyroid desiccated by inhibition of GI absorption. This information does not assure that this product is safe, effective, or appropriate for you. Slowing the infusion rate may alleviate symptoms. Iron Deficiency Anemia: Periodic hematologic determination (hemoglobin and hematocrit) is a simple and accurate technique for monitoring hematological response, and should be used as a guide in therapy. Hemoglobin can be input in g/dL, g/L or mmol/L and refers to the amount of hemoglobin in the red blood cells. iron sucrose decreases levels of gemifloxacin by inhibition of GI absorption. The weight of the patient is taken into account in order to estimate iron stores, while haemoglobin is required as both current measured and target. Applies only to oral form of both agents. Anemias. This topic . Calcs that help predict probability of a disease, Subcategory of 'Diagnosis' designed to be very sensitive, Disease is diagnosed: prognosticate to guide treatment. Administer iron products at least 2 hr before and no less than 6 hr after each dose to avoid chelation with magnesium. ONE DOSE. Adult Dosage and Administration: The recommended dosage of Ferrlecit for the repletion treatment of iron deficiency in hemodialysis patients is 10 mL of Ferrlecit (125 mg of elemental iron). Serious - Use Alternative (1)iron sucrose decreases levels of fleroxacin by inhibition of GI absorption. Iron Product. In post-marketing safety studies of Venofer in 1,051 patients with HDD-CKD, adverse reactions reported by >1% were cardiac failure congestive, sepsis and dysgeusia. iron sucrose decreases levels of ofloxacin by inhibition of GI absorption.

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